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硫酸卡那霉素

点击数:4634
产品类别: 产品分类试剂及培养基德国默克Merck
产品描述:硫酸卡那霉素

产品详情

Description
Overview	Contains more than 98% kanamycin A. An aminoglycoside antibiotic effective against Gram-positive and Gram-negative organisms. Inhibitor of protein biosynthesis that acts on the 30S ribosome, causing misreading of the genetic code. May cause renal damage and ototoxicity.
Overview	Potency: ≥750 µg/mg
Catalogue Number	420311
Brand Family	Calbiochem®
Synonyms	Kamycin

References
References	Lech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., eds.) John Wiley & Sons, New York. Kahn, R.W., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 9295. Cardon, G.H., et al. 1993. Plant J. 3, 773. Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6. Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties 1, 690. Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother. 6, 516. Umezawa, S., et al. 1968. J. Antibiot. 21, 367.

References

Lech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., eds.) John Wiley & Sons, New York.
Kahn, R.W., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 9295.
Cardon, G.H., et al. 1993. Plant J. 3, 773.
Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties 1, 690.
Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother. 6, 516.
Umezawa, S., et al. 1968. J. Antibiot. 21, 367.

Product Information
CAS number	25389-94-0
Form	White to off-white solid
Hill Formula	C₁₈H₃₆N₄O₁₁ · H₂SO₄
Chemical formula	C₁₈H₃₆N₄O₁₁ · H₂SO₄
Molar Mass	582.6
Structure formula Image

Biological Information
Primary Target	protein biosynthesis

Physicochemical Information
Solubility	H₂O

Safety Information according to GHS
RTECS	NZ3225030

Safety Information
R Phrase	R: 61 May cause harm to the unborn child.
S Phrase	S: 26-45 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Carcinogenic / Teratogenic
Storage	+15°C to +30°C
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.